I realize that this is an issue that only has effect on a small subset of users, but being in that subset of users I wish that Apple would do something about this.
I run three monitors at work (my iMac + two 24” Dell UltraSharp displays), and I typically run two at home (my MacBook Pro + one 25” external). And I wish that Apple would introduce some sort of multiple monitor mode to fullscreen apps. Either let each monitor have its own fullscreen mode, or maybe run fullscreen mode as a sort of app carousel, maintaining the existing behavior but letting the Space/Desktop/App to the left and/or right of the primary application in Mission Control live in the monitor to the left or right as well.
Just thoughts, but man I wish fullscreen apps were friendlier for power users.